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中文名稱： 兔抗PHLDA3多克隆抗體
英文名稱： Anti-PHLDA3 rabbit polyclonal antibody
別 名： pleckstrin homology like domain family A member 3; TIH1
相關(guān)類別： 一抗
抗 原： PHLDA3
儲 存： 冷凍（-20℃）
宿 主： Rabbit
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
PHLDA3 |
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Immunogen: |
Fusion protein of human PHLDA3 |
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Full name: |
pleckstrin homology like domain family A member 3 |
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Synonyms: |
TIH1 |
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SwissProt: |
Q9Y5J5 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer and Human thyroid cancer |
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IHC Recommend dilution: |
100-300 |
