Background:

Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes.

Applications:

ELISA, WB

Name of antibody:

BRK1

Immunogen:

Fusion protein of human BRK1

Full name:

BRICK1, SCAR/WAVE actin nucleating complex subunit

Synonyms:

MDS027; hHBrk1; C3orf10; HSPC300

SwissProt:

Q8WUW1

WB Predicted band size:

9 kDa

WB Positive control:

H520 whole cell lysate

WB Recommended dilution:

200-1000