Background:

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined.

Applications:

ELISA, IHC

Name of antibody:

WDR45

Immunogen:

Fusion protein of human WDR45

Full name:

WD repeat domain 45

Synonyms：

JM5; NBIA4; NBIA5; WDRX1; WIPI4; WIPI-4

SwissProt:

Q9Y484

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human prostate cancer and Human thyroid cancer

IHC Recommend dilution:

25-100