Background:

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternatively spliced transcript variants have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

WDR4

Immunogen:

Fusion protein of human WDR4

Full name:

WD repeat domain 4

Synonyms:

TRM82; TRMT82

SwissProt:

P57081

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

50-100

WB Predicted band size:

45 kDa

WB Positive control:

TM4 cell lysate

WB Recommended dilution:

500-2000