Background:

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. This gene encodes the mitochondrial tryptophanyl-tRNA synthetase. Two alternative transcripts encoding different isoforms have been described.

Applications:

ELISA, WB, IHC

Name of antibody:

WARS2

Immunogen:

Fusion protein of human WARS2

Full name:

tryptophanyl tRNA synthetase 2, mitochondrial

Synonyms:

TrpRS

SwissProt:

Q9UGM6

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

40 kDa

WB Positive control:

MCF-7 and Hela cell lysates

WB Recommended dilution:

200-1000