Full name:

2'-5'-oligoadenylate synthetase-like

Synonyms:

OASLd, TRIP14, TRIP-14, p59OASL, p59 OASL, p59-OASL

Swissprot:

Q15646

Gene Accession:

BC117408

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

OASL encodes an interferon-induced protein that is a member of the 2-5A synthetase family. 2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, resulting in general RNA degradation and consequent inhibition of protein synthesis. 2-5As are produced by a well-conserved family of interferon-induced enzymes, the 2-5A synthetases or OASs