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英文名稱： EXO5 Antigen (Recombinant Protein)
別 名： exonuclease 5; DEM1; Exo V; hExo5; C1orf176
儲 存： 冷凍（-20℃）
相關類別： 抗原
概述
|
Fusion protein corresponding to a region derived from 174-373 amino acids of human EXO5 |
|
Full name: |
exonuclease 5 |
|
Synonyms: |
DEM1; Exo V; hExo5; C1orf176 |
|
Swissprot: |
Q9H790 |
|
Gene Accession: |
BC021969 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene is a single-stranded DNA (ssDNA)-specific exonuclease that can slide along the DNA before cutting it. However, human replication protein A binds ssDNA and restricts sliding of the encoded protein, providing a 5'-directionality to the enzyme. This protein localizes to nuclear repair loci after DNA damage. |
